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NanoMuSiC - Nanoparticle and Multielement Quantification in Single Cells: Exploring New Analytical Methods
 
Projektleitung
Dr. rer. nat. Björn Meermann
BAM - 1.1
Anorganische Spurenanalytik
E-Mail: Bjoern.Meermann@bam.de
Förderstruktur
EU - Europäische Kommission - H2020 - Marie S. Curie - Individual Fellowship (IF) - MSCA-IF-2020
Projektbeginn
01.05.2022
Projektende
31.10.2023
Projektart
Realisierte Antragsforschung
Themen-/Aktivitätsfeld
THEMENFELD Analytical Sciences, * Spurenanalytik und chemische Zusammensetzung, ** Single cell- und Single particle-ICP-MS
Abstract
Current analytical methods to measure cellular trace elements or nanoparticles compositions provide information only about the average of the cell populations. An inductively coupled plasma-mass spectrometry (ICP-MS) gains popularity as a tool to evaluate elements and nanoparticles in single cells. The EU-funded NanoMuSiC project will develop highly sensitive analytical methods via coupling a microdroplet generator to ICP-MS for quantification and analysis of the uptake of elements and metal based nanoparticles in single cells. The developed methods will provide proof-of-concept in ecotoxicological applications with diatoms and environmentally relevant elements and nanoparticles, supporting the investigation of potential risks to the environment and human health.
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